MEK-1/2多克隆抗體
| 貨號 | 品牌 | CAS | 規(guī)格 | 銷售價(RMB) | 折扣價(RMB) | 備注 | 數(shù)量 |
| ABP0100-100μL | Abbkine | 無 | 100μL | 1998 | 1998 | 無 |
商品信息
| 產(chǎn)品英文名稱 | MEK-1/2 Polyclonal Antibody |
| 免疫原 | 合成多肽：人源MEK-1/2 非磷酸化位點為中心：S218/222 |
| 宿主 | 兔 |
| 反應(yīng)性 | 人, 大鼠, 小鼠, 猴 |
| 應(yīng)用 | ELISA, IF, IHC-P, WB |
| 實驗建議 | 最佳的工作稀釋比例需要客戶摸索優(yōu)化。建議的起始嘗試的稀釋比為：WB：1:500-1:2000，IF：1:50-1:200，IHC-P：1:50-1:300，ELISA：1:10000-1:20000。 |
| 克隆性 | 多克隆 |
| 純化工藝 | 使用表位特異性的免疫原，通過親和層析，從兔抗血清中親和純化抗體。 |
商品屬性
| 產(chǎn)品形式 | 液體溶液 |
| 濃度 | 1 mg/ml |
| 分子量 | 43 KD |
| 儲存緩沖液 | PBS緩沖液（pH 7.4），含有0.5%BSA（穩(wěn)定劑），0.02％疊氮化鈉（防腐劑）和50％甘油。 |
| 保存建議 | 自發(fā)貨之日起，-20°C可穩(wěn)定保存1年。為最大限度的避免損失，請在打開管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復凍融。 |
| 運輸條件 | 藍冰運輸 |
| 警告 | 本文列出的產(chǎn)品僅供研究使用，不適用于人類或臨床診斷。我們產(chǎn)品所推薦應(yīng)用，不是建議使用我們的產(chǎn)品去違反任何專利或許可證。對于使用本產(chǎn)品可能發(fā)生的專利侵權(quán)或其他違規(guī)行為，我們不承擔任何責任。 |
附加信息
| 背景 | Dual specificity mitogen-activated protein kinase kinase 2 encoded by MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. Dual specificity mitogen-activated protein kinase kinase 2 is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome， a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. |
| 基因ID | 5604/5605 |
| 別名 | MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1; MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein k |
| 其它 | 該抗體可檢測內(nèi)源蛋白 |
| 蛋白質(zhì)ID | Q02750/P36507 |
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