轉(zhuǎn)化生長(zhǎng)因子β1 小鼠單克隆抗體 (10E5)

加入購(gòu)物車

產(chǎn)品英文名稱	TGFβ1 Mouse Monoclonal Antibody (10E5)
免疫原	合成多肽： TGFβ1多肽，310-390位氨基酸
宿主	小鼠
反應(yīng)性	人, 大鼠, 小鼠
應(yīng)用	IHC-P
實(shí)驗(yàn)建議	最佳的工作稀釋比例需要客戶摸索優(yōu)化。建議的起始嘗試的稀釋比為：IHC-p：1:100-200。
克隆性	單克隆
純化工藝	使用表位特異性的免疫原，通過親和層析，從小鼠腹水中親和純化抗體。

產(chǎn)品形式	液體溶液
濃度	1 mg/ml
儲(chǔ)存緩沖液	含有50％甘油，0.5％BSA和0.02％疊氮化鈉的PBS緩沖液。
保存建議	自發(fā)貨之日起，-20°C可穩(wěn)定保存1年。為最大限度的避免損失，請(qǐng)?jiān)诖蜷_管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復(fù)凍融。
運(yùn)輸條件	藍(lán)冰運(yùn)輸
警告	本文列出的產(chǎn)品僅供研究使用，不適用于人類或臨床診斷。我們產(chǎn)品所推薦應(yīng)用，不是建議使用我們的產(chǎn)品去違反任何專利或許可證。對(duì)于使用本產(chǎn)品可能發(fā)生的專利侵權(quán)或其他違規(guī)行為，我們不承擔(dān)任何責(zé)任。

背景	TGFB1 (transforming growth factor beta 1) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. TGFB1 is frequently upregulated in tumor cells, and mutations in TGFB1 result in Camurati-Engelmann disease.
基因ID	7040
別名	TGFB1
其它	該抗體可檢測(cè)內(nèi)源蛋白
蛋白質(zhì)ID	P01137
目標(biāo)條帶分子量（KD)	12,25,45-65